---
title: Adverse Effect in One-Third of Prescription Medications is Depression
description: Depression Studies and Mental Health | for those who use more than 3 medications are at risk for Depression. Mental Health is important.
image: https://www.maryaprn.com/hubfs/cartoon_art/animated_people/exhausted-collection-tom-004.png
---

![Depression](https://www.maryaprn.com/hubfs/cartoon_art/animated_people/exhausted-collection-tom-004.png)

## ![Depression](https://www.maryaprn.com/hs-fs/hubfs/cartoon_art/animated_people/exhausted-collection-tom-004.png?width=279&name=exhausted-collection-tom-004.png)Mental Health and Depression | The Prevalence of depression is higher for adults reporting use of multiple meds.

The estimated prevalence of using medications with depression as an adverse effect is 37.2%, according to a study published in the June 12 issue of the Journal of the American Medical Association.

Depression and Mental Health | Dima Mazen Qato, PharmD, MPH, PhD, from the University of Illinois at Chicago, and colleagues analyzed five 2-year cycles of the National Health and Nutrition Examination Survey (2005-2006 through 2013-2014) for use of prescription medications with depression as a potential adverse effect.

The researchers found that 7.6% of the 26,192 adults reported depression. The overall estimated prevalence was 37.2% for use of medications with depression as an adverse effect, which increased from 35.0 to 38.4% from 2005-2006 to 2013-2014.

![Depression](https://www.maryaprn.com/hs-fs/hubfs/Health-12.png?width=100&name=Health-12.png)Reported use of 3 or more concurrent medications with a potential for depression as an adverse effect was estimated at 6.9% in 2005 and 2006 and 9.5% in 2013 and 2014. The number of medications used with depression as a possible adverse effect correlated with increased prevalence of concurrent depression, in analyses excluding antidepressant users.

The estimated prevalence of depression was 15% vs 4.7% for those reporting use of 3 or more medications with depression as an adverse effect vs those not using such medications.

"Use of multiple medications was associated with greater likelihood of concurrent depression," the authors write.

[*Source:*](https://www.clinicaladvisor.com/mood-disorder-information-center/depression-an-adverse-effect-in-one-third-of-prescription-medications/article/773080/?utm_source=newsletter&utm_medium=email&utm_campaign=ca-update-20180614&dl=0&DCMP=EMC-ca-update-20180614&cpn=Latuda82474HH%2clatuda16284%2cpsych_nppa%2clat_ad%2cpsych_all%2clatcaHCHL%2calkscore%2cpch_108941%2cmiralax_110603%2clat_92058HCHL&hmSubId=Zokkx_oH18o1&hmEmail=FAq8UQpvEVOBC_iXBzVI9jIZDo7e_i8h0&NID=1033285564&spMailingID=19738117&spUserID=MTkwMDA1MDk1MDMS1&spJobID=1280769593&spReportId=MTI4MDc2OTU5MwS2)

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